angiopoietin-2
- Definition
- An angiopoietin that is closely related to angiopoietin-1. It binds to the TIE-2 receptor without receptor stimulation and antagonizes the effect of angiopoietin-1. However its antagonistic effect may be limited to cell receptors that occur within the vasculature. Angiopoietin-2 may therefore play a role in down-regulation of blood vessel branching and sprouting.
- Definition Source
- Medical Subject Headings 2014
- Spanish
- angiopoyetina-2
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