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NAL Agricultural Thesaurus and Glossary
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buprenorphine
Subject Category
H Health and Pathology
W Physical and Chemical Sciences
Definition
A derivative of the opioid alkaloid thebaine that is a more potent and longer lasting analgesic than morphine. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.
Definition Source
Medical Subject Headings 2012
RDF/XML Format:
http://lod.nal.usda.gov/nalt/8452.rdf
Persistent URI:
http://lod.nal.usda.gov/nalt/8452
Used For
buprenorphine hydrochloride
Broader Term
analgesics
opium alkaloids
Spanish
buprenorfina
Term Number
8452